Varaico: Literature-Extracted Genetic Variants

Gene:FEN1
Variant:p.E359K
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FEN1

NM_004111.6:p.E359K

Associated Papers

The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation.

Sun H et al.

Oncogene, 2017

Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.

Zhou L et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2017

Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.

He L et al.

Ebiomedicine, 2016

The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.

Chung L et al.

Oncogene, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."