Varaico: Literature-Extracted Genetic Variants

Gene:FGB
Variant:p.R285H
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FGB

NM_005141.5:p.R285H

Associated Papers

-455A Allele May Be a Protective Locus for Aseptic Lower Extremity Superficial Thrombophlebitis.

Luo R et al.

Genetic Testing and Molecular Biomarkers, 2025

Fibrinogen B β promoter polymorphism may not be associated with pulmonary embolism.

Chen W et al.

Phlebology, 2024

The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140 214 UK Biobank participants.

Stefanucci L et al.

Blood, 2023

37647632 (PubMed )
Supplement: BLOOD_BLD-2023-020118-mmc3.xlsx › ST3.4

Associations Between 25-Hydroxyvitamin D and Total and γ' Fibrinogen and Plasma Clot Properties and Gene Interactions in a Group of Healthy Black South African Women.

Rautenbach PH et al.

Frontiers in Cardiovascular Medicine, 2022

An association between fibrinogen gene polymorphisms and diabetic peripheral neuropathy in young patients with type 1 diabetes.

Vojtková J et al.

Molecular Biology Reports, 2021

A rare heterozygous variant in FGB (Fibrinogen Merivale) causing hypofibrinogenemia in a Swedish family.

Fager Ferrari M et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2020

Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations.

Cronjé HT et al.

Plos One, 2017

A polymorphism (-455G>A) in the β-fibrinogen gene is associated with an increased risk of cerebral infarction in the Chinese population: A meta-analysis.

Cheng SY et al.

Journal of the Renin-angiotensin-aldosterone System : Jraas, 2015

FGB mutations leading to congenital quantitative fibrinogen deficiencies: an update and report of four novel mutations.

Casini A et al.

Thrombosis Research, 2014

Genetic polymorphism of β-fibrinogen gene-455G/A can contribute to the risk of ischemic stroke.

Gu L et al.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014

Fibrinogen and cardiovascular disease: genetics and biomarkers.

Tousoulis D et al.

Blood Reviews, 2011

Influence of fibrinogen beta-chain gene variations on risk of myocardial infarction in a Chinese Han population.

Lu XF et al.

Chinese Medical Journal, 2008

Identification and functional characterization of a polymorphic oestrogen response element in the human coagulation factor IX gene promoter.

Adams B et al.

British Journal of Haematology, 2008

Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese population.

Xu X et al.

Cerebrovascular Diseases (basel, Switzerland), 2008

Fibrinogen-beta gene haplotype is associated with mortality in sepsis.

Manocha S et al.

The Journal of Infection, 2007

Mutations in the fibrinogen gene cluster accounting for congenital afibrinogenemia: an update and report of 10 novel mutations.

Neerman-Arbez M et al.

Human Mutation, 2007

Genetic factors contribute to bleeding after cardiac surgery.

Welsby IJ et al.

Journal of Thrombosis and Haemostasis : Jth, 2005

Genetics of thrombophilia: impact on atherogenesis.

Voetsch B et al.

Current Opinion in Lipidology, 2004

Congenital afibrinogenemia: identification and expression of a missense mutation in FGB impairing fibrinogen secretion.

Vu D et al.

Blood, 2003

Angiotensin-converting enzyme genotype, albuminuria and plasma fibrinogen in type 2 diabetes mellitus.

Tkác I et al.

Wiener Klinische Wochenschrift, 2003

[Preliminary study on single nucleotide polymorphisms and linkage disequilibrium in promoter region of fibrinogen B beta gene].

Gong WX et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2003

Fibrinogen polymorphisms and atherothrombotic disease.

Green FR

Annals of the New York Academy of Sciences, 2001

Genetic aspects of ischemic stroke: coagulation, homocysteine, and lipoprotein metabolism as potential risk factors.

Stankovic S et al.

Critical Reviews in Clinical Laboratory Sciences, 0

Relational analysis among fibrinogenic Bβ-chain gene polymorphisms and its functional expression and obesity.

Xiaodong Y et al.

Obesity Research & Clinical Practice, 0

The Correlation Between FGB Promoter Polymorphism and Clotting Function in Patients With Idiopathic Lower Extremity Deep Venous Thrombosis.

Han S et al.

Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."