Varaico: Literature-Extracted Genetic Variants

Gene:FGF19
Variant:p.H33L
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FGF19

NM_005117.3:p.H33L

Associated Papers

Therapeutic FGF19 promotes HDL biogenesis and transhepatic cholesterol efflux to prevent atherosclerosis.

Zhou M et al.

Journal of Lipid Research, 2019

Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis.

Gadaleta RM et al.

Scientific Reports, 2018

Engineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice.

Zhou M et al.

Hepatology (baltimore, Md.), 2016

A nontumorigenic variant of FGF19 treats cholestatic liver diseases.

Luo J et al.

Science Translational Medicine, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."