Varaico: Literature-Extracted Genetic Variants

Gene:FGFR1
Variant:p.K656M
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FGFR1

NM_023110.3:p.K656M

Associated Papers

Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations.

Tangermann C et al.

Nature Genetics, 2026

41361008 (PubMed )
Supplement: 41588_2025_2431_MOESM6_ESM.xlsx › Figure_E10a

Concurrence of FGFR1 mutations modulates oncogenesis in glioneuronal tumors.

Boni J et al.

The Embo Journal, 2025

41174249 (PubMed )
Supplement: 44318_2025_600_MOESM1_ESM.pdf

Biological and clinical implications of FGFR aberrations in paediatric and young adult cancers.

Brown LM et al.

Oncogene, 2023

The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations.

Villani A et al.

Nature Cancer, 2023

Association of the FGFR1 mutation with spontaneous hemorrhage in low-grade gliomas in pediatric and young adult patients.

Ishi Y et al.

Journal of Neurosurgery, 2021

Adult pilocytic astrocytoma in the molecular era: a comprehensive review.

Gregory TA et al.

Cns Oncology, 2021

Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W.

Chae YK et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2020

Septal dysembryoplastic neuroepithelial tumor: a comprehensive clinical, imaging, histopathologic, and molecular analysis.

Chiang JCH et al.

Neuro-oncology, 2019

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM2_ESM.xlsx › Sheet1

Genetic alterations related to BRAF-FGFR genes and dysregulated MAPK/ERK/mTOR signaling in adult pilocytic astrocytoma.

Pathak P et al.

Brain Pathology (zurich, Switzerland), 2017

ESR1 ligand-binding domain mutations in hormone-resistant breast cancer.

Toy W et al.

Nature Genetics, 2013

24185512 (PubMed )
Supplement: NIHMS531250-supplement-2.xlsx › All_samples_N_36_

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Jones DT et al.

Nature Genetics, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."