Varaico: Literature-Extracted Genetic Variants

Gene:FGFR1
Variant:p.Y563C
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FGFR1

NM_023110.3:p.Y563C

Associated Papers

Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations.

Tangermann C et al.

Nature Genetics, 2026

41361008 (PubMed )
Supplement: 41588_2025_2431_MOESM3_ESM.xlsx › S10_Screen_data_table

The role of fibroblast growth factor receptor (FGFR) protein-tyrosine kinase inhibitors in the treatment of cancers including those of the urinary bladder.

Roskoski R

Pharmacological Research, 2020

Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting.

Farrell B et al.

Biochemical Society Transactions, 2018

The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study.

Bunney TD et al.

Ebiomedicine, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."