Varaico: Literature-Extracted Genetic Variants

Gene:FGFR2
Variant:p.I642V
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FGFR2

NM_000141.5:p.I642V

Associated Papers

Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations.

Tangermann C et al.

Nature Genetics, 2026

41361008 (PubMed )
Supplement: 41588_2025_2431_MOESM5_ESM.xlsx › Figure_2e

Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy.

von Baumgarten L et al.

Theranostics, 2020

31903155 (PubMed )
Supplement: thnov10p0856s1.pdf

FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review).

Katoh M

International Journal of Molecular Medicine, 2016

Standardized decision support in next generation sequencing reports of somatic cancer variants.

Dienstmann R et al.

Molecular Oncology, 2014

Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Dixit A et al.

Computational and Mathematical Methods in Medicine, 2014

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials.

Lovly CM et al.

Plos One, 2012

FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies.

Katoh M

The Journal of Investigative Dermatology, 2009

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma.

Gartside MG et al.

Molecular Cancer Research : Mcr, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."