Varaico: Literature-Extracted Genetic Variants

Gene:FGFR2
Variant:p.V395D
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FGFR2

NM_000141.5:p.V395D

Associated Papers

Integrating evidence from protein domains to identify cancer driver mutations.

Ostroverkhova D et al.

Protein Science : a Publication of the Protein Society, 2026

41556616 (PubMed )
Supplement: PRO-35-e70422-s002.xlsx › Table_S1

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

Prevalence and clinicopathological correlation of BRAF V600E mutations in ameloblastoma: A PCR study from a tertiary centre in South India.

Jayamani L et al.

Journal of Stomatology, Oral and Maxillofacial Surgery, 2025

Functional Characterization of Variants of Unknown Significance of Fibroblast Growth Factor Receptors 1-4 and Comparison With AI Model-Based Prediction.

Ziegler M et al.

Jco Precision Oncology, 2025

Novel NRAS G12D mutation in extraosseous/peripheral ameloblastoma: Case report and review of mitogen-activated protein kinase pathway mutations in extraosseous/peripheral and intraosseous ameloblastomas.

Oh KY et al.

Journal of Dental Sciences, 2024

Pemigatinib in previously treated solid tumors with activating FGFR1-FGFR3 alterations: phase 2 FIGHT-207 basket trial.

Rodón J et al.

Nature Medicine, 2024

38710951 (PubMed )
Supplement: 41591_2024_2934_MOESM1_ESM.pdf

Development, testing and validation of a targeted NGS-panel for the detection of actionable mutations in lung cancer (NSCLC) using anchored multiplex PCR technology in a multicentric setting.

Kumbrink J et al.

Pathology Oncology Research : Por, 2024

38605929 (PubMed )
Supplement: Table1.XLSX › Sup_Table_1_Comparison_details

Oncogenic activation revealed by FGFR2 genetic alterations in intrahepatic cholangiocarcinomas.

Pu X et al.

Cell & Bioscience, 2023

Postzygotic gain-of-function variants in FGFR2 in two patients with hair follicle naevus.

Cheng Q et al.

The British Journal of Dermatology, 2023

Precision medicine: Sustained response to erdafitinib in FGFR2-mutant, multiply recurrent ameloblastoma.

Lawson-Michod KA et al.

Cancer Reports (hoboken, N.j.), 2022

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

Zingg D et al.

Nature, 2022

35948633 (PubMed )
Supplement: 41586_2022_5066_MOESM16_ESM.xlsx › ED_Fig._2a

Cerebriform sebaceous nevus: a subtype of organoid nevus due to specific postzygotic FGFR2 mutations.

Theiler M et al.

Journal of the European Academy of Dermatology and Venereology : Jeadv, 2021

A review of the use of next generation sequencing methodologies to identify biomarkers of resistance to CDK4/6 inhibitors in ER+/HER2- breast cancer.

Servetto A et al.

Critical Reviews in Oncology/hematology, 2021

A Pancancer Analysis of the Expression Landscape and Clinical Relevance of Fibroblast Growth Factor Receptor 2 in Human Cancers.

Li J et al.

Frontiers in Oncology, 2021

33968743 (PubMed )
Supplement: Table_2.XLSX › table

The Molecular Pathology of Odontogenic Tumors: Expanding the Spectrum of MAPK Pathway Driven Tumors.

Guimarães LM et al.

Frontiers in Oral Health, 2021

Genetic Profile of Adenomatoid Odontogenic Tumor and Ameloblastoma. A Systematic Review.

Marín C et al.

Frontiers in Oral Health, 2021

Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W.

Chae YK et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2020

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer.

Formisano L et al.

Nature Communications, 2019

Genomic landscape of salivary gland tumors.

Kato S et al.

Oncotarget, 2015

26247885 (PubMed )
Supplement: oncotarget-06-25631-s002.xlsx › Sheet1

Functions of Fibroblast Growth Factor Receptors in cancer defined by novel translocations and mutations.

Gallo LH et al.

Cytokine & Growth Factor Reviews, 2015

Ameloblastoma: A Review of Recent Molecular Pathogenetic Discoveries.

Brown NA et al.

Biomarkers in Cancer, 2015

Activating FGFR2-RAS-BRAF mutations in ameloblastoma.

Brown NA et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014

FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.

Byron SA et al.

Plos One, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."