Varaico: Literature-Extracted Genetic Variants

Gene:FGFR2
Variant:p.D336N
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FGFR2

NM_000141.5:p.D336N

Associated Papers

A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.

Apfelbaum AA et al.

Nature Communications, 2025

40744913 (PubMed )
Supplement: 41467_2025_61820_MOESM11_ESM.pdf

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

Zingg D et al.

Nature, 2022

35948633 (PubMed )
Supplement: 41586_2022_5066_MOESM16_ESM.xlsx › ED_Fig._2a

Virtual screening on an α-helix to β-strand switchable region of the FGFR2 extracellular domain revealed positive and negative modulators.

Diaz C et al.

Proteins, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."