Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.R175H
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FGFR3

NM_000142.5:p.R175H

Associated Papers

A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib.

Shi Y et al.

Signal Transduction and Targeted Therapy, 2025

41326340 (PubMed )
Supplement: 41392_2025_2481_MOESM1_ESM.docx

Somatic mutation and selection at population scale.

Lawson ARJ et al.

Nature, 2025

41062696 (PubMed )
Supplement: 41586_2025_9584_MOESM1_ESM.pdf

Clinical relevance of the somatic mutational landscaping in predicting outcome of bladder cancer patients.

Nedjadi T et al.

Scientific Reports, 2025

Influence of TP53 mutation on efficacy and survival in advanced EGFR-mutant non-small cell lung cancer patients treated with third-generation EGFR tyrosine kinase inhibitors.

Zhang Z et al.

Medcomm, 2024

38832214 (PubMed )
Supplement: MCO2-5-e586-s001.docx

Whole-genome mapping of APOBEC mutagenesis in metastatic urothelial carcinoma identifies driver hotspot mutations and a novel mutational signature.

Nakauma-González JA et al.

Cell Genomics, 2024

38552621 (PubMed )
Supplement: mmc11.pdf

The correlation between clinical outcomes and genomic analysis with high risk factors for the progression of osteosarcoma.

Liu W et al.

Molecular Oncology, 2024

37727135 (PubMed )
Supplement: MOL2-18-939-s001.pdf

Analysis of the benefit of anti-PD-1 monotherapy according to NGS-diagnosed genetic alterations in patients with non-small cell lung cancer.

De Saint Basile H et al.

Exploration of Targeted Anti-tumor Therapy, 2024

Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment.

Song Y et al.

Journal for Immunotherapy of Cancer, 2023

37777251 (PubMed )
Supplement: jitc-2022-006643supp001.pdf

Clinicopathologic Characteristics and Outcomes for Patients With KRAS G12D-Mutant NSCLC.

Cooper AJ et al.

Jto Clinical and Research Reports, 2022

36118132 (PubMed )
Supplement: mmc2.docx

Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma.

Shohdy KS et al.

British Journal of Cancer, 2022

Next-generation sequencing-based identification of EGFR and NOTCH2 complementary mutations in non-small cell lung cancer.

Niu L et al.

Oncology Letters, 2021

Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients.

Tsui DWY et al.

Genome Medicine, 2021

34059130 (PubMed )
Supplement: 13073_2021_898_MOESM3_ESM.xlsx › SuppTable1

Enhancing the landscape of colorectal cancer using targeted deep sequencing.

Lee CS et al.

Scientific Reports, 2021

Identifying therapeutic drug targets using bidirectional effect genes.

Estrada K et al.

Nature Communications, 2021

33850126 (PubMed )
Supplement: 41467_2021_21843_MOESM7_ESM.xlsx › Supplementary_Data_6

TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients.

Pandey R et al.

Cancers, 2021

Exosome-based detection of EGFR T790M in plasma and pleural fluid of prospectively enrolled non-small cell lung cancer patients after first-line tyrosine kinase inhibitor therapy.

Kim Y et al.

Cancer Cell International, 2021

33435996 (PubMed )
Supplement: 12935_2021_1761_MOESM1_ESM.docx

Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic.

Williams EA et al.

Acta Neuropathologica Communications, 2020

33087175 (PubMed )
Supplement: 40478_2020_1040_MOESM1_ESM.xlsx › Sheet1

Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Egan C et al.

Haematologica, 2020

Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma.

Nakagaki T et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2018

Genetic characterisation of molecular targets in carcinoma of unknown primary.

Clynick B et al.

Journal of Translational Medicine, 2018

Identification of frequent somatic mutations in inflammatory breast cancer.

Matsuda N et al.

Breast Cancer Research and Treatment, 2017

RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients.

Kato S et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

27683183 (PubMed )
Supplement: 10780432ccr161679-sup-168576_1_supp_3636667_wcc1ns.docx

Rapid detection of genetic mutations in individual breast cancer patients by next-generation DNA sequencing.

Liu S et al.

Human Genomics, 2015

Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.

Millis SZ et al.

Clinical Genitourinary Cancer, 2015

Mapping the p53 transcriptome universe using p53 natural polymorphs.

Wang B et al.

Cell Death and Differentiation, 2014

Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.

Zanaruddin SN et al.

Plos One, 2013

Fresh surgical specimens yield breast stem/progenitor cells and reveal their oncogenic abnormalities.

Pommier SJ et al.

Annals of Surgical Oncology, 2012

21748247 (PubMed )
Supplement: 10434_2011_1892_MOESM2_ESM.pdf

SNU cell lines and their application for cancer research.

Park JG

Gan to Kagaku Ryoho. Cancer & Chemotherapy, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."