Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.I538F
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FGFR3

NM_000142.5:p.I538F

Associated Papers

Assembly mechanism of early Hsp90-Cdc37-kinase complexes.

Keramisanou D et al.

Science Advances, 2022

Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting.

Farrell B et al.

Biochemical Society Transactions, 2018

Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.

Bunney TD et al.

Structure (london, England : 1993), 2018

Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use.

Patani H et al.

Oncotarget, 2016

The paradox of FGFR3 signaling in skeletal dysplasia: why chondrocytes growth arrest while other cells over proliferate.

Krejci P

Mutation Research. Reviews in Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."