Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.V553M
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FGFR3

NM_000142.5:p.V553M

Associated Papers

Harnessing genomic profiling for improved urothelial cancer outcomes.

Yu EM et al.

Expert Review of Anticancer Therapy, 2026

Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations.

Tangermann C et al.

Nature Genetics, 2026

41361008 (PubMed )
Supplement: 41588_2025_2431_MOESM3_ESM.xlsx › S7_Reported_resistance

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6

Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.

Bhérer C et al.

Medrxiv : the Preprint Server for Health Sciences, 2025

40791678 (PubMed )
Supplement: media-2.xlsx › Table_S12_ClinVar_PLP_variants

FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies.

Noeraparast M et al.

Cancer Communications (london, England), 2024

Pemigatinib for metastatic or surgically unresectable urothelial carcinoma with FGF/FGFR genomic alterations: final results from FIGHT-201.

Necchi A et al.

Annals of Oncology : Official Journal of the European Society for Medical Oncology, 2024

Clinical-genetic analysis of selected genes involved in the development of the human skeleton in 128 Czech patients with suspected congenital skeletal abnormalities.

Spurná Z et al.

Gene, 2024

Clinical and Genomic Landscape of FGFR3-Altered Urothelial Carcinoma and Treatment Outcomes with Erdafitinib: A Real-World Experience.

Guercio BJ et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2023

Resistance to Selective FGFR Inhibitors in FGFR-Driven Urothelial Cancer.

Facchinetti F et al.

Cancer Discovery, 2023

Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinoma.

Kendre G et al.

Journal of Hepatology, 2023

Genomic heterogeneity as a barrier to precision oncology in urothelial cancer.

Clinton TN et al.

Cell Reports, 2022

Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers.

Suzuki T et al.

Oncotarget, 2020

32922660 (PubMed )
Supplement: oncotarget-11-3198-s002.xlsx › Table_1

Selfish mutations dysregulating RAS-MAPK signaling are pervasive in aged human testes.

Maher GJ et al.

Genome Research, 2018

30355600 (PubMed )
Supplement: supp_gr.239186.118_Supplemental_Table_S3.xlsx › Table_of_prioritized_calls
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."