Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.V553L
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FGFR3

NM_000142.5:p.V553L

Associated Papers

Saturation mutagenesis identifies activating and resistance-inducing FGFR kinase domain mutations.

Tangermann C et al.

Nature Genetics, 2026

41361008 (PubMed )
Supplement: 41588_2025_2431_MOESM3_ESM.xlsx › S7_Reported_resistance

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6

Resistance to Selective FGFR Inhibitors in FGFR-Driven Urothelial Cancer.

Facchinetti F et al.

Cancer Discovery, 2023

Diagnostic yield of a multigene sequencing approach in children classified as idiopathic short stature.

Andrade NLM et al.

Endocrine Connections, 2022

Genomic variation as a marker of response to neoadjuvant therapy in locally advanced rectal cancer.

Douglas JK et al.

Molecular & Cellular Oncology, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."