Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.E565A
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FGFR3

NM_000142.5:p.E565A

Associated Papers

Rational Design and Identification of ISM7594 as a Tissue-Agnostic FGFR2/3 Inhibitor.

Wang Y et al.

Journal of Medicinal Chemistry, 2025

A Phase I Study of KIN-3248, an Irreversible Small-molecule Pan-FGFR Inhibitor, in Patients with Advanced FGFR2/3-driven Solid Tumors.

Garmezy B et al.

Cancer Research Communications, 2024

38602417 (PubMed )
Supplement: crc-24-0137-s07.pdf

Elucidating the Role of Wildtype and Variant FGFR2 Structural Dynamics in (Dys)Function and Disorder.

Lian Y et al.

International Journal of Molecular Sciences, 2024

Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases.

Chen H et al.

Elife, 2017

Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Dixit A et al.

Computational and Mathematical Methods in Medicine, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."