Varaico: Literature-Extracted Genetic Variants

Gene:FGFR3
Variant:p.K650R
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FGFR3

NM_000142.5:p.K650R

Associated Papers

Prevalence and biological impact of clinically relevant gene fusions in head and neck cancers.

Hoskins EL et al.

Npj Precision Oncology, 2025

40610725 (PubMed )
Supplement: 41698_2025_889_MOESM5_ESM.xlsx › Sheet1

Computational analysis reveals histotype-dependent molecular profile and actionable mutation effects across cancers.

Heim D et al.

Genome Medicine, 2018

30442178 (PubMed )
Supplement: 13073_2018_591_MOESM4_ESM.xlsx › Table_S2

Differential regulation of FGFR3 by PTPN1 and PTPN2.

St-Germain JR et al.

Proteomics, 2015

Activating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumors.

Goriely A et al.

Nature Genetics, 2009

Distinct missense mutations of the FGFR3 lys650 codon modulate receptor kinase activation and the severity of the skeletal dysplasia phenotype.

Bellus GA et al.

American Journal of Human Genetics, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."