Associated Papers
Integrated morphological, immunohistochemical, and genomic profiling identifies uterine leiomyoma patients with hereditary leiomyomatosis and renal cell cancer syndrome: a comprehensive analysis of 252 cases.
Liu Y et al.
The Journal of Pathology, 2026
A Case of a Fumarate Hydratase Deficient Astrocytoma in Association With a Germline Fumarate Hydratase Mutation With Review of the Literature: Considerations for Patients With Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) Syndrome.
Alfattal R et al.
The American Journal of Surgical Pathology, 2026
Fumarate hydratase-mutant glioma with giant-cell histology, MSH6 mutation, and hypermutation.
Mafficini A et al.
Journal of Neuropathology and Experimental Neurology, 2025
Long survival in a patient with fumarate hydratase mutation-associated glioma.
Reimann RR et al.
Journal of Neuropathology and Experimental Neurology, 2025
Germline and Somatic Fumarate Hydratase Testing in Atypical Uterine Leiomyomata.
Kipnis LM et al.
Cancer Prevention Research (philadelphia, Pa.), 2024
Mutations of FH and IDH may induce gliomagenesis by similar mechanisms.
Raghunathan A et al.
Journal of Neuropathology and Experimental Neurology, 2022
Uterine leiomyomas in hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome can be identified through distinct clinical characteristics and typical morphology.
Uimari O et al.
Acta Obstetricia Et Gynecologica Scandinavica, 2021
Targeted sequencing of FH-deficient uterine leiomyomas reveals biallelic inactivating somatic fumarase variants and allows characterization of missense variants.
Popp B et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2020
Expanding morphological and clinical aspects of hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a case report in a patient with unusual morphology and clinical presentation.
da Cunha IW et al.
Virchows Archiv : an International Journal of Pathology, 2018
MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas.
Kämpjärvi K et al.
British Journal of Cancer, 2016
Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings.
Harrison WJ et al.
The American Journal of Surgical Pathology, 2016
Clonally related uterine leiomyomas are common and display branched tumor evolution.
Mehine M et al.
Human Molecular Genetics, 2015
Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.
Tolvanen J et al.
Human Reproduction (oxford, England), 2012