Varaico: Literature-Extracted Genetic Variants

Gene:FHIT
Variant:p.Y114F
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FHIT

NM_002012.4:p.Y114F

Associated Papers

The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport.

Sjölander JJ et al.

Cell Biology International, 2020

Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions.

Pichiorri F et al.

The Journal of Biological Chemistry, 2009

Restoration of fragile histidine triad expression restores Chk2 activity in response to ionizing radiation in oral squamous cell carcinoma cells.

Yutori H et al.

Cancer Science, 2008

Fhit modulates the DNA damage checkpoint response.

Ishii H et al.

Cancer Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."