Associated Papers
Inhibition of FicD-mediated AMPylation and deAMPylation by Isoprenoid Diphosphates.
Blevins AM et al.
Biorxiv : the Preprint Server for Biology, 2025
FIC Domain Protein Adenylyltransferase (FICD)-Related Complex Hereditary Spastic Paraplegia with Diabetes Mellitus.
Rebelo AP et al.
Movement Disorders Clinical Practice, 2025
Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity.
Van Pelt KM et al.
Plos Genetics, 2025
Pre-clinical model of dysregulated FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis.
Casey AK et al.
Molecular Metabolism, 2025
Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation.
Chatterjee BK et al.
Acs Chemical Biology, 2025
Dysregulation of FicD AMPylation causes diabetes by disrupting pancreatic endocrine homeostasis.
Casey AK et al.
Biorxiv : the Preprint Server for Biology, 2024
Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation.
Chatterjee BK et al.
Biorxiv : the Preprint Server for Biology, 2024
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP.
Perera LA et al.
Embo Molecular Medicine, 2023
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