Varaico: Literature-Extracted Genetic Variants

Gene:FKBP5
Variant:p.D68V
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FKBP5

NM_004117.4:p.D68V

Associated Papers

A protein engineering approach toward understanding FKBP51 conformational dynamics and mechanisms of ligand binding.

Lerma Romero JA et al.

Protein Engineering, Design & Selection : Peds, 2023

Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins.

LeMaster DM et al.

The Journal of Biological Chemistry, 2015

The helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones.

Cluning C et al.

Molecular Endocrinology (baltimore, Md.), 2013

FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.

Wochnik GM et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."