Associated Papers
Improved genomic characterization of a clinically heterogeneous pediatric cohort with WGS vs. WES.
Brashear AM et al.
Scientific Reports, 2025
Filaggrin loss-of-function variants are associated with atopic dermatitis phenotypes in a diverse, early-life prospective cohort.
Virolainen SJ et al.
Jci Insight, 2024
Influence of pathogenic filaggrin variants on dupilumab treatment in atopic dermatitis.
Clabbers J et al.
The Journal of Allergy and Clinical Immunology, 2024
Phase separation as a possible mechanism for dosage sensitivity.
Yang L et al.
Genome Biology, 2024
In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers.
Paul AA et al.
Frontiers in Molecular Biosciences, 2023
The Skin and Nose Microbiome and Its Association with Filaggrin Gene Mutations in Pediatric Atopic Dermatitis.
van Mierlo MMF et al.
Dermatology (basel, Switzerland), 2022
The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.
Cao Y et al.
Cell Research, 2020
Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes.
Capalbo A et al.
Plos Genetics, 2019
Uncommon Filaggrin Variants Are Associated with Persistent Atopic Dermatitis in African Americans.
Margolis DJ et al.
The Journal of Investigative Dermatology, 2018
Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic.
Foley SB et al.
Ebiomedicine, 2015
Genetic susceptibility for cow's milk allergy in Dutch children: the start of the allergic march?
Henneman P et al.
Clinical and Translational Allergy, 2015
Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production.
Thyssen JP et al.
Evolutionary Biology, 2014
Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
Wang Y et al.
Nature, 2014
Integrated analysis of germline and somatic variants in ovarian cancer.
Kanchi KL et al.
Nature Communications, 2014
Filaggrin mutations associated with skin and allergic diseases.
Irvine AD et al.
The New England Journal of Medicine, 2011
Associations of FLG mutations between ichthyosis vulgaris and atopic dermatitis in Han Chinese.
Zhang H et al.
Allergy, 2011
Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.
Chen H et al.
The British Journal of Dermatology, 2011
Full sequencing of the FLG gene in Italian patients with atopic eczema: evidence of new mutations, but lack of an association.
Cascella R et al.
The Journal of Investigative Dermatology, 2011
Mutations in the filaggrin gene in Han Chinese patients with atopic dermatitis.
Zhang H et al.
Allergy, 2011
Filaggrin gene defects and the risk of developing allergic disorders.
Osawa R et al.
Allergology International : Official Journal of the Japanese Society of Allergology, 2011
Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes.
O'Regan GM et al.
The Journal of Allergy and Clinical Immunology, 2010
Novel and recurrent mutations in the filaggrin gene in Chinese patients with ichthyosis vulgaris.
Zhang X et al.
The British Journal of Dermatology, 2010
FLG mutations in ichthyosis vulgaris and atopic eczema: spectrum of mutations and population genetics.
Akiyama M
The British Journal of Dermatology, 2010
FLG mutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese patients with atopic eczema.
Nemoto-Hasebe I et al.
The British Journal of Dermatology, 2009
Ichthyosis vulgaris: novel FLG mutations in the German population and high presence of CD1a+ cells in the epidermis of the atopic subgroup.
Oji V et al.
The British Journal of Dermatology, 2009
Filaggrin and the great epidermal barrier grief.
McGrath JA
The Australasian Journal of Dermatology, 2008
Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis.
Sandilands A et al.
The Journal of Investigative Dermatology, 2007
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema.
Sandilands A et al.
Nature Genetics, 2007
Filaggrin Gene Mutation in Pediatric Patients with Atopic Dermatitis: A Look into Indian Gene Pool, a Pilot Study.
Rajeshwari KA et al.
Indian Journal of Dermatology, 0
Neonatal Filaggrin Genetic Screening and Counseling to Prevent Atopic Dermatitis in High-Risk Infants.
Chen HY et al.
Dermatitis : Contact, Atopic, Occupational, Drug, 0