Associated Papers
Trajectories of egg sensitization in childhood: Two birth cohorts in Asia and Europe.
Nakamura T et al.
Allergy, 2025
Novel loss-of-function variants in filaggrin exon 3 in patients with severe atopic dermatitis.
Bellinato F et al.
Archives of Dermatological Research, 2024
Phase separation as a possible mechanism for dosage sensitivity.
Yang L et al.
Genome Biology, 2024
In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers.
Paul AA et al.
Frontiers in Molecular Biosciences, 2023
Revisiting the Roles of Filaggrin in Atopic Dermatitis.
Moosbrugger-Martinz V et al.
International Journal of Molecular Sciences, 2022
Early-life predictors and risk factors of peanut allergy, and its association with asthma in later-life: Population-based birth cohort study.
Kotsapas C et al.
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2022
Modelling trajectories of parentally reported and physician-confirmed atopic dermatitis in a birth cohort study.
Nakamura T et al.
The British Journal of Dermatology, 2022
Whole genome sequencing identifies novel genetic mutations in patients with eczema herpeticum.
Bin L et al.
Allergy, 2021
Filaggrin gene mutations with special reference to atopic dermatitis.
Gupta J et al.
Current Treatment Options in Allergy, 2020
Early-life inhalant allergen exposure, filaggrin genotype, and the development of sensitization from infancy to adolescence.
Simpson A et al.
The Journal of Allergy and Clinical Immunology, 2020
Spectrum of ichthyoses in an Austrian ichthyosis cohort from 2004 to 2017.
Seidl-Philipp M et al.
Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : Jddg, 2020
Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis.
Haftek M et al.
Wellcome Open Research, 2020
Variation at DENND1B and Asthma on the Island of Tristan da Cunha.
Duffy DL et al.
Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies, 2019
Filaggrin mutations increase allergic airway disease in childhood and adolescence through interactions with eczema and aeroallergen sensitization.
Chan A et al.
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2018
The study of filaggrin gene mutations and copy number variation in atopic dermatitis patients from Volga-Ural region of Russia.
Gimalova GF et al.
Gene, 2016
Investigation of Skin Barrier Functions and Allergic Sensitization in Patients with Hyper-IgE Syndrome.
Mócsai G et al.
Journal of Clinical Immunology, 2015
Association of common filaggrin null mutations with atopy but not chronic rhinosinusitis.
Mahdavinia M et al.
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 2015
Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiency.
Gruber R et al.
The American Journal of Pathology, 2015
Genetic susceptibility for cow's milk allergy in Dutch children: the start of the allergic march?
Henneman P et al.
Clinical and Translational Allergy, 2015
Filaggrin mutations in a Western siberian population and their association with atopic dermatitis in children.
Komova EG et al.
Genetic Testing and Molecular Biomarkers, 2014
Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence.
Venkataraman D et al.
The Journal of Allergy and Clinical Immunology, 2014
Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production.
Thyssen JP et al.
Evolutionary Biology, 2014
Severe skin inflammation and filaggrin mutation similarly alter the skin barrier in patients with atopic dermatitis.
Mócsai G et al.
The British Journal of Dermatology, 2014
Association between P478S polymorphism of the filaggrin gene & atopic dermatitis.
Kim SY et al.
The Indian Journal of Medical Research, 2013
A familial study of filaggrin mutation in atopic dermatitis.
Mohiuddin MS et al.
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology, 2013
Ichthyosis vulgaris: the filaggrin mutation disease.
Thyssen JP et al.
The British Journal of Dermatology, 2013
The 420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation: implications for atopic dermatitis.
Fortugno P et al.
Human Molecular Genetics, 2012
One remarkable molecule: filaggrin.
Brown SJ et al.
The Journal of Investigative Dermatology, 2012
Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.
Ziyab AH et al.
Plos One, 2012
Filaggrin mutations associated with skin and allergic diseases.
Irvine AD et al.
The New England Journal of Medicine, 2011
[Association of filaggrin gene polymorphism with atopic dermatitis in southern Chinese Han population].
Li CX et al.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2011
Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.
Chen H et al.
The British Journal of Dermatology, 2011
Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.
Gruber R et al.
The American Journal of Pathology, 2011
Full sequencing of the FLG gene in Italian patients with atopic eczema: evidence of new mutations, but lack of an association.
Cascella R et al.
The Journal of Investigative Dermatology, 2011
Distinct barrier integrity phenotypes in filaggrin-related atopic eczema following sequential tape stripping and lipid profiling.
Angelova-Fischer I et al.
Experimental Dermatology, 2011
Filaggrin gene defects and the risk of developing allergic disorders.
Osawa R et al.
Allergology International : Official Journal of the Japanese Society of Allergology, 2011
Loss-of-function mutations within the filaggrin gene and atopic dermatitis.
Kawasaki H et al.
Current Problems in Dermatology, 2011
A prospective study of filaggrin null mutations in keratoconus patients with or without atopic disorders.
Droitcourt C et al.
Dermatology (basel, Switzerland), 2011
Raman profiles of the stratum corneum define 3 filaggrin genotype-determined atopic dermatitis endophenotypes.
O'Regan GM et al.
The Journal of Allergy and Clinical Immunology, 2010
Novel and recurrent mutations in the filaggrin gene in Chinese patients with ichthyosis vulgaris.
Zhang X et al.
The British Journal of Dermatology, 2010
FLG mutations in ichthyosis vulgaris and atopic eczema: spectrum of mutations and population genetics.
Akiyama M
The British Journal of Dermatology, 2010
Association analysis of filaggrin gene mutations and atopic dermatitis in Northern China.
Ma L et al.
The British Journal of Dermatology, 2010
Human leukocyte antigen (DR1)-DQB1*0501 and (DR15)-DQB1*0602 haplotypes are associated with humoral responses to early food allergens in children.
Savilahti EM et al.
International Archives of Allergy and Immunology, 2010
FLG mutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese patients with atopic eczema.
Nemoto-Hasebe I et al.
The British Journal of Dermatology, 2009
Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure.
Schuttelaar ML et al.
Allergy, 2009
Filaggrin mutations may confer susceptibility to chronic hand eczema characterized by combined allergic and irritant contact dermatitis.
Molin S et al.
The British Journal of Dermatology, 2009
Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.
Brown SJ et al.
The British Journal of Dermatology, 2009
Analysis of Taiwanese ichthyosis vulgaris families further demonstrates differences in FLG mutations between European and Asian populations.
Hsu CK et al.
The British Journal of Dermatology, 2009