Varaico: Literature-Extracted Genetic Variants

Gene:FLG
Variant:p.Q1225delFs
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FLG

NM_002016.2:p.Q1225delFs

Associated Papers

Trajectories of egg sensitization in childhood: Two birth cohorts in Asia and Europe.

Nakamura T et al.

Allergy, 2025

In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers.

Paul AA et al.

Frontiers in Molecular Biosciences, 2023

37200867 (PubMed )
Supplement: Table1.DOCX

Revisiting the Roles of Filaggrin in Atopic Dermatitis.

Moosbrugger-Martinz V et al.

International Journal of Molecular Sciences, 2022

Early-life predictors and risk factors of peanut allergy, and its association with asthma in later-life: Population-based birth cohort study.

Kotsapas C et al.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2022

Modelling trajectories of parentally reported and physician-confirmed atopic dermatitis in a birth cohort study.

Nakamura T et al.

The British Journal of Dermatology, 2022

Early-life inhalant allergen exposure, filaggrin genotype, and the development of sensitization from infancy to adolescence.

Simpson A et al.

The Journal of Allergy and Clinical Immunology, 2020

Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production.

Thyssen JP et al.

Evolutionary Biology, 2014

Ichthyosis vulgaris: the filaggrin mutation disease.

Thyssen JP et al.

The British Journal of Dermatology, 2013

Filaggrin mutations associated with skin and allergic diseases.

Irvine AD et al.

The New England Journal of Medicine, 2011

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

Brown SJ et al.

The British Journal of Dermatology, 2009

Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: systematic review and meta-analysis.

van den Oord RA et al.

Bmj (clinical Research Ed.), 2009

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