Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.Y842F
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FLT3

NM_004119.3:p.Y842F

Associated Papers

Understanding the characteristic behaviour of the wild-type and mutant structure of FLT3 protein by computational methods.

Younus S et al.

Computational and Structural Biotechnology Journal, 2025

Understanding the Role of Activation Loop Mutants in Drug Efficacy for FLT3-ITD.

Kazi JU et al.

Cancers, 2023

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD.

Kazi JU et al.

Cellular and Molecular Life Sciences : Cmls, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."