Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.Y842S
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FLT3

NM_004119.3:p.Y842S

Associated Papers

Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia.

Gutierrez-Camino A et al.

British Journal of Cancer, 2024

38049555 (PubMed )
Supplement: 41416_2023_2511_MOESM1_ESM.pdf

Deciphering the molecular mechanism of FLT3 resistance mutations.

Georgoulia PS et al.

The Febs Journal, 2020

Genetic mutational analysis of pediatric acute lymphoblastic leukemia from a single center in China using exon sequencing.

Zhang H et al.

Bmc Cancer, 2020

Profiling FLT3 Mutations in Mexican Acute Myeloid Leukemia Pediatric Patients: Impact on Overall Survival.

Molina Garay C et al.

Frontiers in Pediatrics, 2020

Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.

Falini B et al.

British Journal of Haematology, 2015

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397.

Smith CC et al.

Cancer Discovery, 2015

FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro.

von Bubnoff N et al.

Cancer Research, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."