Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.N841H
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FLT3

NM_004119.3:p.N841H

Associated Papers

Novel molecular mechanisms of FLT3 deregulation: from the acute myeloid leukemia experience to therapeutic insights in acute lymphoblastic leukemia.

Lo Schiavo F et al.

Molecular Cancer, 2025

41126239 (PubMed )
Supplement: 12943_2025_2455_MOESM2_ESM.xlsx › Table_S1

Landscape of FLT3 Variations Associated with Structural and Functional Impact on Acute Myeloid Leukemia: A Computational Study.

Mirza Z et al.

International Journal of Molecular Sciences, 2024

Gilteritinib is a clinically active FLT3 inhibitor with broad activity against FLT3 kinase domain mutations.

Tarver TC et al.

Blood Advances, 2020

Parallel targeted next generation sequencing of childhood and adult acute myeloid leukemia patients reveals uniform genomic profile of the disease.

Marjanovic I et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

FLT3 K663Q is a novel AML-associated oncogenic kinase: Determination of biochemical properties and sensitivity to Sunitinib (SU11248).

Schittenhelm MM et al.

Leukemia, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."