Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.C695S
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FLT3

NM_004119.3:p.C695S

Associated Papers

The Irreversible FLT3 Inhibitor FF-10101 Is Active Against a Diversity of FLT3 Inhibitor Resistance Mechanisms.

Ferng TT et al.

Molecular Cancer Therapeutics, 2022

Modulation of FLT3 signal transduction through cytoplasmic cysteine residues indicates the potential for redox regulation.

Böhmer A et al.

Redox Biology, 2020

A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells with FLT3 mutations.

Yamaura T et al.

Blood, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."