Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.Y591D
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FLT3

NM_004119.3:p.Y591D

Associated Papers

Unveiling splicing disruptions due to common somatic variants in acute myeloid leukemia.

Morote-Faubel M et al.

Human Genomics, 2025

41189001 (PubMed )
Supplement: 40246_2025_842_MOESM1_ESM.pdf

Leveraging genomic diagnostics for prognostics and therapeutics in pediatric acute leukemia.

Newman H et al.

Hemasphere, 2025

41306327 (PubMed )
Supplement: HEM3-9-e70269-s013.xlsx › Supplemental_Table_5_-_SSVs

Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis.

Wen S et al.

Nature Genetics, 2025

39948438 (PubMed )
Supplement: 41588_2025_2085_MOESM4_ESM.xlsx › ST_4

Landscape of FLT3 Variations Associated with Structural and Functional Impact on Acute Myeloid Leukemia: A Computational Study.

Mirza Z et al.

International Journal of Molecular Sciences, 2024

Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia.

Gutierrez-Camino A et al.

British Journal of Cancer, 2024

38049555 (PubMed )
Supplement: 41416_2023_2511_MOESM1_ESM.pdf

Clinical and molecular features of FLT3 juxtamembrane domain missense mutations in acute myeloid leukaemia.

Jensen CE et al.

Journal of Cellular and Molecular Medicine, 2022

Genomic Abnormalities as Biomarkers and Therapeutic Targets in Acute Myeloid Leukemia.

Ribeiro S et al.

Cancers, 2021

Panel-based next-generation sequencing facilitates the characterization of childhood acute myeloid leukemia in clinical settings.

Ishida H et al.

Biomedical Reports, 2020

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.

Rothenberg-Thurley M et al.

Leukemia, 2018

29472724 (PubMed )
Supplement: 41375_2018_34_MOESM2_ESM.xlsx › Supplemental_Table_3

The modular network structure of the mutational landscape of Acute Myeloid Leukemia.

Ibáñez M et al.

Plos One, 2018

30303964 (PubMed )
Supplement: pone.0202926.s006.pdf

Four novel point mutations in exons 12, 13, and 14 of the FLT3 gene.

Syampurnawati M et al.

Leukemia Research, 2007

Point mutations in the juxtamembrane domain of FLT3 define a new class of activating mutations in AML.

Reindl C et al.

Blood, 2006

Novel FLT3 point mutations within exon 14 found in patients with acute myeloid leukaemia.

Stirewalt DL et al.

British Journal of Haematology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."