Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.L576R
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FLT3

NM_004119.3:p.L576R

Associated Papers

Novel molecular mechanisms of FLT3 deregulation: from the acute myeloid leukemia experience to therapeutic insights in acute lymphoblastic leukemia.

Lo Schiavo F et al.

Molecular Cancer, 2025

41126239 (PubMed )
Supplement: 12943_2025_2455_MOESM2_ESM.xlsx › Table_S1

Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia.

Gutierrez-Camino A et al.

British Journal of Cancer, 2024

Mutation spectrum of FLT3 and significance of non-canonical FLT3 mutations in haematological malignancy.

Ge SS et al.

British Journal of Haematology, 2023

Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.

Umeda M et al.

Blood Cancer Discovery, 2022

35176137 (PubMed )
Supplement: bcd-21-0160_supplemental_tables_supp1-32.xlsx › Table_S12_SNV_indel

Successful nelarabine and venetoclax treatment of a relapsed/refractory mediastinal myeloid sarcoma with clonal TCR rearrangement.

Contejean A et al.

Anti-cancer Drugs, 2021

The mutational spectrum of FLT3 gene in acute lymphoblastic leukemia is different from acute myeloid leukemia.

Zhang Y et al.

Cancer Gene Therapy, 2020

FLT3 Mutations in Acute Myeloid Leukemia: Key Concepts and Emerging Controversies.

Kennedy VE et al.

Frontiers in Oncology, 2020

Nanopore Targeted Sequencing for Rapid Gene Mutations Detection in Acute Myeloid Leukemia.

Cumbo C et al.

Genes, 2019

Clonal and microclonal mutational heterogeneity in high hyperdiploid acute lymphoblastic leukemia.

de Smith AJ et al.

Oncotarget, 2016

27683039 (PubMed )
Supplement: oncotarget-07-72733-s003.xlsx › Sheet1

[Detection of point mutation at second tyrosine kinase domain of FLT3 gene in acute myeloid leukemia].

Wang LH et al.

Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."