Varaico: Literature-Extracted Genetic Variants

Gene:FLT3
Variant:p.Y572F
Back to variants list

FLT3

NM_004119.3:p.Y572F

Associated Papers

FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia.

Kazi JU et al.

Molecular Oncology, 2013

Transformation by oncogenic mutants and ligand-dependent activation of FLT3 wild-type requires the tyrosine residues 589 and 591.

Vempati S et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."