Varaico: Literature-Extracted Genetic Variants

Gene:FMO3
Variant:p.N61K
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FMO3

NM_001002294.3:p.N61K

Associated Papers

Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease.

Phillips IR et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020

Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.

Teitelbaum AM et al.

The Pharmacogenomics Journal, 2018

Clinical utility gene card for: Trimethylaminuria - update 2014.

Shephard EA et al.

European Journal of Human Genetics : Ejhg, 2015

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.

Yamazaki H et al.

Biochemical Pharmacology, 2013

Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.

Christodoulou J

Journal of Paediatrics and Child Health, 2012

Clinical utility gene card for: trimethylaminuria.

Shephard EA et al.

European Journal of Human Genetics : Ejhg, 2012

Flavin-containing monooxygenases: mutations, disease and drug response.

Phillips IR et al.

Trends in Pharmacological Sciences, 2008

Flavin-containing monooxygenase 3 and human disease.

Motika MS et al.

Expert Opinion on Drug Metabolism & Toxicology, 2007

Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3).

Allerston CK et al.

Pharmacogenetics and Genomics, 2007

Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.

Yeung CK et al.

Archives of Biochemistry and Biophysics, 2007

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.

Koukouritaki SB et al.

The Journal of Pharmacology and Experimental Therapeutics, 2007

Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.

Koukouritaki SB et al.

Molecular Pharmacology, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."