Varaico: Literature-Extracted Genetic Variants

Gene:FMO3
Variant:p.G148*
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FMO3

NM_001002294.3:p.G148*

Associated Papers

In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.

Shimizu M et al.

Biological & Pharmaceutical Bulletin, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing.

Guo Y et al.

Bmc Medical Genetics, 2017

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.

Yamazaki H et al.

Biochemical Pharmacology, 2013

Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.

Christodoulou J

Journal of Paediatrics and Child Health, 2012

Flavin-containing monooxygenase 3 and human disease.

Motika MS et al.

Expert Opinion on Drug Metabolism & Toxicology, 2007

The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development.

Cashman JR

Drug Discovery Today, 2004

Trimethylaminuria and a human FMO3 mutation database.

Hernandez D et al.

Human Mutation, 2003

Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.

Zhang J et al.

Pharmacogenetics, 2003

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.

Cashman JR et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2002

Phenotyping of flavin-containing monooxygenase using caffeine metabolism and genotyping of FMO3 gene in a Korean population.

Park CS et al.

Pharmacogenetics, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."