Associated Papers
Identification of Poor Prognostic Markers in Triple-Negative Breast Cancer Using Whole Exome Sequencing.
Lee S et al.
Journal of Breast Cancer, 2025
In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.
Shimizu M et al.
Biological & Pharmaceutical Bulletin, 2025
Exploring Trimethylaminuria: Genetics and Molecular Mechanisms, Epidemiology, and Emerging Therapeutic Strategies.
Sidoti A et al.
Biology, 2024
Variants of Flavin-Containing Monooxygenase 3 Found in Subjects in an Updated Database of Genome Resources.
Makiguchi M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023
A series of simple detection systems for genetic variants of flavin-containing monooxygenase 3 (FMO3) with impaired function in Japanese subjects.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2021
Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease.
Phillips IR et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2020
Novel variants and haplotypes of human flavin-containing monooxygenase 3 gene associated with Japanese subjects suffering from trimethylaminuria.
Shimizu M et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2019
A compound heterozygous mutation in the FMO3 gene: the first pediatric case causes fish odor syndrome in Korea.
Kim JH et al.
Korean Journal of Pediatrics, 2017
Human flavin-containing monooxygenase 3: Structural mapping of gene polymorphisms and insights into molecular basis of drug binding.
Gao C et al.
Gene, 2016
Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3.
Okubo M et al.
Human Psychopharmacology, 2016
Analysis of six novel flavin-containing monooxygenase 3 (FMO3) gene variants found in a Japanese population suffering from trimethylaminuria.
Shimizu M et al.
Molecular Genetics and Metabolism Reports, 2015
Clinical utility gene card for: Trimethylaminuria - update 2014.
Shephard EA et al.
European Journal of Human Genetics : Ejhg, 2015
Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.
Shimizu M et al.
British Journal of Clinical Pharmacology, 2014
Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.
Yamazaki H et al.
Biochemical Pharmacology, 2013
Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Shimizu M et al.
Molecular Genetics and Metabolism, 2012
Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.
Christodoulou J
Journal of Paediatrics and Child Health, 2012
Allelic analyses of the Arabidopsis YUC1 locus reveal residues and domains essential for the functions of YUC family of flavin monooxygenases.
Hou X et al.
Journal of Integrative Plant Biology, 2011
[Individual differences of drug-metabolizing enzymes as determinants for the metabolic fate of chemicals--a study of trimethylamine and flavin-containing monooxygenase 3-].
Shimizu M
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan, 2009
Inter-individual variation in flavin-containing monooxygenase 3 in livers from Japanese: correlation with hepatic transcription factors.
Nagashima S et al.
Drug Metabolism and Pharmacokinetics, 2009
Flavin-containing monooxygenase 3 and human disease.
Motika MS et al.
Expert Opinion on Drug Metabolism & Toxicology, 2007
Molecular evolution and balancing selection in the flavin-containing monooxygenase 3 gene (FMO3).
Allerston CK et al.
Pharmacogenetics and Genomics, 2007
Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (fish odor syndrome): observations from Japanese patients.
Yamazaki H et al.
Current Drug Metabolism, 2007
Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities.
Shimizu M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Yamazaki H et al.
Molecular Genetics and Metabolism, 2007
Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism.
Krueger SK et al.
Pharmacology & Therapeutics, 2005