Associated Papers
In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.
Shimizu M et al.
Biological & Pharmaceutical Bulletin, 2025
Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2023
Variants of Flavin-Containing Monooxygenase 3 Found in Subjects in an Updated Database of Genome Resources.
Makiguchi M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2023
A family study of compound variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found by urinary phenotyping for trimethylaminuria.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2023
Pervasive occurrence of splice-site-creating mutations and their possible involvement in genetic disorders.
Sakaguchi N et al.
Npj Genomic Medicine, 2022
A series of simple detection systems for genetic variants of flavin-containing monooxygenase 3 (FMO3) with impaired function in Japanese subjects.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2021
Novel variants and haplotypes of human flavin-containing monooxygenase 3 gene associated with Japanese subjects suffering from trimethylaminuria.
Shimizu M et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2019
Genetic variants of flavin-containing monooxygenase 3 (FMO3) derived from Japanese subjects with the trimethylaminuria phenotype and whole-genome sequence data from a large Japanese database.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2019
Analysis of six novel flavin-containing monooxygenase 3 (FMO3) gene variants found in a Japanese population suffering from trimethylaminuria.
Shimizu M et al.
Molecular Genetics and Metabolism Reports, 2015
Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.
Shimizu M et al.
British Journal of Clinical Pharmacology, 2014
Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.
Yamazaki H et al.
Biochemical Pharmacology, 2013
Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Shimizu M et al.
Molecular Genetics and Metabolism, 2012
Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.
Christodoulou J
Journal of Paediatrics and Child Health, 2012
[Individual differences of drug-metabolizing enzymes as determinants for the metabolic fate of chemicals--a study of trimethylamine and flavin-containing monooxygenase 3-].
Shimizu M
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan, 2009
Flavin-containing monooxygenase 3 and human disease.
Motika MS et al.
Expert Opinion on Drug Metabolism & Toxicology, 2007
Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (fish odor syndrome): observations from Japanese patients.
Yamazaki H et al.
Current Drug Metabolism, 2007
Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities.
Shimizu M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Yamazaki H et al.
Molecular Genetics and Metabolism, 2007