Varaico: Literature-Extracted Genetic Variants

Gene:FMO3
Variant:p.E314*
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FMO3

NM_001002294.3:p.E314*

Associated Papers

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing.

Pierce SE et al.

Nature, 2025

41261131 (PubMed )
Supplement: 41586_2025_9732_MOESM17_ESM.xlsx › Sequence_Context_Screen

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Molecular cloning, sequence characterization, SNP detection, and tissue expression analysis of duck FMO3 gene.

Wang P et al.

Molecular and Cellular Biochemistry, 2013

Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.

Yamazaki H et al.

Biochemical Pharmacology, 2013

Quail FMO3 gene cloning, tissue expression profiling, polymorphism detection and association analysis with fishy taint in eggs.

Mo F et al.

Plos One, 2013

Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.

Christodoulou J

Journal of Paediatrics and Child Health, 2012

Flavin-containing monooxygenase 3 and human disease.

Motika MS et al.

Expert Opinion on Drug Metabolism & Toxicology, 2007

Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism.

Krueger SK et al.

Pharmacology & Therapeutics, 2005

The implications of polymorphisms in mammalian flavin-containing monooxygenases in drug discovery and development.

Cashman JR

Drug Discovery Today, 2004

Trimethylaminuria and a human FMO3 mutation database.

Hernandez D et al.

Human Mutation, 2003

Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.

Zhang J et al.

Pharmacogenetics, 2003

A nonsense mutation in the FMO3 gene underlies fishy off-flavor in cow's milk.

Lundén A et al.

Genome Research, 2002

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation.

Cashman JR et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2002

Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome.

Dolphin CT et al.

Pharmacogenetics, 2000

Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.

Akerman BR et al.

Molecular Genetics and Metabolism, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."