Associated Papers
In Silico Binary Classification of Catalytic Function (Unaffected or Impaired) of Flavin-Containing Monooxygenase 3 (FMO3) Variants and in Vitro Validation Using New Variants Found in a Japanese Genome Resource Database.
Shimizu M et al.
Biological & Pharmaceutical Bulletin, 2025
Exploring Trimethylaminuria: Genetics and Molecular Mechanisms, Epidemiology, and Emerging Therapeutic Strategies.
Sidoti A et al.
Biology, 2024
Rare but impaired flavin-containing monooxygenase 3 (FMO3) variants reported in a recently updated Japanese mega-databank of genome resources.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2024
First Report from Saudi Arabia of Trimethylaminuria Caused by a Premature Stop Codon Mutation in the FMO3 Gene.
Alghanem B et al.
The Application of Clinical Genetics, 2024
Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2023
A series of simple detection systems for genetic variants of flavin-containing monooxygenase 3 (FMO3) with impaired function in Japanese subjects.
Shimizu M et al.
Drug Metabolism and Pharmacokinetics, 2021
Novel variants and haplotypes of human flavin-containing monooxygenase 3 gene associated with Japanese subjects suffering from trimethylaminuria.
Shimizu M et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2019
A compound heterozygous mutation in the FMO3 gene: the first pediatric case causes fish odor syndrome in Korea.
Kim JH et al.
Korean Journal of Pediatrics, 2017
Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3.
Okubo M et al.
Human Psychopharmacology, 2016
Analysis of six novel flavin-containing monooxygenase 3 (FMO3) gene variants found in a Japanese population suffering from trimethylaminuria.
Shimizu M et al.
Molecular Genetics and Metabolism Reports, 2015
Clinical utility gene card for: Trimethylaminuria - update 2014.
Shephard EA et al.
European Journal of Human Genetics : Ejhg, 2015
Relationships between flavin-containing mono-oxygenase 3 (FMO3) genotype and trimethylaminuria phenotype in a Japanese population.
Shimizu M et al.
British Journal of Clinical Pharmacology, 2014
Survey of variants of human flavin-containing monooxygenase 3 (FMO3) and their drug oxidation activities.
Yamazaki H et al.
Biochemical Pharmacology, 2013
Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Shimizu M et al.
Molecular Genetics and Metabolism, 2012
Trimethylaminuria: an under-recognised and socially debilitating metabolic disorder.
Christodoulou J
Journal of Paediatrics and Child Health, 2012
[Individual differences of drug-metabolizing enzymes as determinants for the metabolic fate of chemicals--a study of trimethylamine and flavin-containing monooxygenase 3-].
Shimizu M
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan, 2009
Novel variants of the human flavin-containing monooxygenase 3 (FMO3) gene associated with trimethylaminuria.
Motika MS et al.
Molecular Genetics and Metabolism, 2009
Flavin-containing monooxygenase 3 and human disease.
Motika MS et al.
Expert Opinion on Drug Metabolism & Toxicology, 2007
Genetic polymorphism of the flavin-containing monooxygenase 3 (FMO3) associated with trimethylaminuria (fish odor syndrome): observations from Japanese patients.
Yamazaki H et al.
Current Drug Metabolism, 2007
Effect of genetic variants of the human flavin-containing monooxygenase 3 on N- and S-oxygenation activities.
Shimizu M et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007
Transient trimethylaminuria related to menstruation.
Shimizu M et al.
Bmc Medical Genetics, 2007
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Yamazaki H et al.
Molecular Genetics and Metabolism, 2007