Associated Papers
Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity.
King J et al.
Cell Reports, 2025
41124077 (PubMed )
Supplement: NIHMS2125804-supplement-2.xlsx › TableS1B
FOXC2 Disease Mutations Identified in Lymphedema Distichiasis Patients Impair Transcriptional Activity and Cell Proliferation.
Tavian D et al.
International Journal of Molecular Sciences, 2020
Structural basis for DNA recognition by FOXC2.
Chen X et al.
Nucleic Acids Research, 2019
Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders.
Sollis E et al.
Human Mutation, 2017
In silico analysis of single nucleotide polymorphisms (SNPs) in human FOXC2 gene.
Nimir M et al.
F1000research, 2017
FOXC2 disease-mutations identified in lymphedema-distichiasis patients cause both loss and gain of protein function.
Tavian D et al.
Oncotarget, 2016
FOXC2 and FLT4 Gene Variants in Lymphatic Filariasis.
Sheik Y et al.
Lymphatic Research and Biology, 2015
A five generation family with a novel mutation in FOXC2 and lymphedema worsening to hydrops in the youngest generation.
Sargent C et al.
American Journal of Medical Genetics. Part A, 2014
Novel missense mutations in the FOXC2 gene alter transcriptional activity.
van Steensel MA et al.
Human Mutation, 2009
Missense mutations in the forkhead domain of FOXL2 lead to subcellular mislocalization, protein aggregation and impaired transactivation.
Beysen D et al.
Human Molecular Genetics, 2008
Research perspectives in inherited lymphatic disease: an update.
Ferrell RE et al.
Annals of the New York Academy of Sciences, 2008
Functional genetic analysis of mutations implicated in a human speech and language disorder.
Vernes SC et al.
Human Molecular Genetics, 2006
The establishment of a predictive mutational model of the forkhead domain through the analyses of FOXC2 missense mutations identified in patients with hereditary lymphedema with distichiasis.
Berry FB et al.
Human Molecular Genetics, 2005
Lymphoedema-distichiasis and FOXC2: unreported mutations, de novo mutation estimate, families without coding mutations.
Sholto-Douglas-Vernon C et al.
Human Genetics, 2005
Analysis of the phenotypic abnormalities in lymphoedema-distichiasis syndrome in 74 patients with FOXC2 mutations or linkage to 16q24.
Brice G et al.
Journal of Medical Genetics, 2002
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