Associated Papers
Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity.
King J et al.
Cell Reports, 2025
Informed clinical decisions by outfoxing human FOXN1 variants.
Wysocki CA et al.
The Journal of Allergy and Clinical Immunology, 2025
Utilization of next-generation sequencing to define the role of heterozygous FOXN1 variants in immunodeficiency.
Pasternak Y et al.
The Journal of Allergy and Clinical Immunology. Global, 2024
Comprehensive phenotypic analysis of diverse FOXN1 variants.
Moses A et al.
The Journal of Allergy and Clinical Immunology, 2023
FOXN1 Gene Considerations in Severe Combined Immunodeficiency Treatment in Children.
Torres S et al.
Cureus, 2022
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Rota IA et al.
Science Advances, 2021
Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations.
Giardino G et al.
Journal of Clinical Immunology, 2021
Inborn errors of thymic stromal cell development and function.
Kreins AY et al.
Seminars in Immunopathology, 2021
FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.
Du Q et al.
The Journal of Clinical Investigation, 2019
Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis.
Bosticardo M et al.
American Journal of Human Genetics, 2019
Epstein-Barr virus associated with high-grade B-cell lymphoma in nude severe combined immunodeficiency.
Albar R et al.
Bmj Case Reports, 2019
A Novel FOXN1 Variant Is Identified in Two Siblings with Nude Severe Combined Immunodeficiency.
Firtina S et al.
Journal of Clinical Immunology, 2019
FOXN1 Deficiency: from the Discovery to Novel Therapeutic Approaches.
Gallo V et al.
Journal of Clinical Immunology, 2017
FOXN1 deficient nude severe combined immunodeficiency.
Rota IA et al.
Orphanet Journal of Rare Diseases, 2017
Rapid molecular diagnostics of severe primary immunodeficiency determined by using targeted next-generation sequencing.
Yu H et al.
The Journal of Allergy and Clinical Immunology, 2016
Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies.
D'Assante R et al.
International Reviews of Immunology, 2016
Severe combined immunodeficiency--an update.
Cirillo E et al.
Annals of the New York Academy of Sciences, 2015
A novel mutation in FOXN1 resulting in SCID: a case report and literature review.
Chou J et al.
Clinical Immunology (orlando, Fla.), 2014
FOXN1 in organ development and human diseases.
Palamaro L et al.
International Reviews of Immunology, 2014
FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program.
Romano R et al.
Frontiers in Immunology, 2013
[Post-thymus transplant vitiligo in a child with Foxn1 deficiency].
Levy E et al.
Annales De Dermatologie Et De Venereologie, 2012
Human FOXN1-deficiency is associated with αβ double-negative and FoxP3+ T-cell expansions that are distinctly modulated upon thymic transplantation.
Albuquerque AS et al.
Plos One, 2012
First use of thymus transplantation therapy for FOXN1 deficiency (nude/SCID): a report of 2 cases.
Markert ML et al.
Blood, 2011
Dental treatment of children with severe combined immunodeficiency.
Moyer IN et al.
Pediatric Dentistry, 1983