Varaico: Literature-Extracted Genetic Variants

Gene:FOXO1
Variant:p.S256A
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FOXO1

NM_002015.4:p.S256A

Associated Papers

FOXO1 is a master regulator of CAR T memory programming.

Doan A et al.

Research Square, 2023

ABCA9, an ER cholesterol transporter, inhibits breast cancer cell proliferation via SREBP-2 signaling.

Hwang HJ et al.

Cancer Science, 2023

Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin.

Mao H et al.

Nature Communications, 2021

Targeted sequencing reveals the mutational landscape responsible for sorafenib therapy in advanced hepatocellular carcinoma.

Tang J et al.

Theranostics, 2020

32373219 (PubMed )
Supplement: thnov10p5384s2.xlsx › S4-AllCellLineMut

Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma.

Hu Q et al.

Plos One, 2013

Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.

Di Pietro N et al.

Molecular Endocrinology (baltimore, Md.), 2010

Aberrant Forkhead box O1 function is associated with impaired hepatic metabolism.

Qu S et al.

Endocrinology, 2006

Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism.

Kortylewski M et al.

The Journal of Biological Chemistry, 2003

Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.

Zhang BH et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."