Associated Papers
Clonal hematopoiesis is associated with distinct rheumatoid arthritis phenotypes.
Hiitola E et al.
Science Advances, 2025
Identification of genetic subtypes in follicular lymphoma.
Shelton V et al.
Blood Cancer Journal, 2024
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution.
Asante Y et al.
Nature Communications, 2023
FOXO1 is a master regulator of CAR T memory programming.
Doan A et al.
Research Square, 2023
Noncanonical CDK4 signaling rescues diabetes in a mouse model by promoting β cell differentiation.
Stamateris RE et al.
The Journal of Clinical Investigation, 2023
ABCA9, an ER cholesterol transporter, inhibits breast cancer cell proliferation via SREBP-2 signaling.
Hwang HJ et al.
Cancer Science, 2023
The discrete roles of individual FOXO transcription factor family members in B-cell malignancies.
Lees J et al.
Frontiers in Immunology, 2023
FOXA1 is a transcriptional activator of Odf2/Cenexin and regulates primary ciliation.
Czerny CC et al.
Scientific Reports, 2022
Molecular subclusters of follicular lymphoma: a report from the United Kingdom's Haematological Malignancy Research Network.
Crouch S et al.
Blood Advances, 2022
Diagnostic value of genetic mutation analysis and mutation profiling of cell-free DNA in intraocular fluid for vitreoretinal lymphoma.
Chen X et al.
Cancer Communications (london, England), 2022
A pilot study of the use of dynamic analysis of cell-free DNA from aqueous humor and vitreous fluid for the diagnosis and treatment monitoring of vitreoretinal lymphomas.
Wang X et al.
Haematologica, 2022
Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab.
Bruscaggin A et al.
Blood Advances, 2021
Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin.
Mao H et al.
Nature Communications, 2021
Targeted next generation sequencing reveals high mutation frequency of CREBBP, BCL2 and KMT2D in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements.
Evrard SM et al.
Haematologica, 2019
PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression.
Park MK et al.
Nature Communications, 2019
Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma.
González-Rincón J et al.
Plos One, 2019
WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis.
Sreekumar A et al.
Developmental Cell, 2017
Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas.
Morin RD et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016
Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.
Yalley A et al.
The Journal of Biological Chemistry, 2016
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis.
Menghini R et al.
Atherosclerosis, 2015
Analysis of FOXO1 mutations in diffuse large B-cell lymphoma.
Trinh DL et al.
Blood, 2013
Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma.
Hu Q et al.
Plos One, 2013
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.
Morin RD et al.
Nature, 2011
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.
Fan W et al.
The Embo Journal, 2010
Serum- and glucocorticoid-inducible kinase 1 (SGK1) regulates adipocyte differentiation via forkhead box O1.
Di Pietro N et al.
Molecular Endocrinology (baltimore, Md.), 2010
Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism.
Kortylewski M et al.
The Journal of Biological Chemistry, 2003
Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.
Zhang BH et al.
The Journal of Biological Chemistry, 2001
Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR.
Nakae J et al.
The Embo Journal, 2000
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.
Nakae J et al.
The Journal of Biological Chemistry, 1999