Associated Papers
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging.
Jing Y et al.
Protein & Cell, 2023
Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia.
Panelli P et al.
Blood, 2023
36315912 (PubMed )
Supplement: BLOOD_BLD-2022-017079-mmc4.pdf
TLR4 (toll-like receptor 4) activation suppresses autophagy through inhibition of FOXO3 and impairs phagocytic capacity of microglia.
Lee JW et al.
Autophagy, 2019
PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression.
Park MK et al.
Nature Communications, 2019
Geminin facilitates FoxO3 deacetylation to promote breast cancer cell metastasis.
Zhang L et al.
The Journal of Clinical Investigation, 2017
Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers.
Cheong JK et al.
The Journal of Clinical Investigation, 2015
Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop.
Kannike K et al.
The Journal of Biological Chemistry, 2014
FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop.
Lützner N et al.
Plos One, 2012
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport.
Brunet A et al.
The Journal of Cell Biology, 2002
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