Varaico: Literature-Extracted Genetic Variants

Gene:FOXO4
Variant:p.S162C
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FOXO4

NM_005938.4:p.S162C

Associated Papers

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

Bourgeois B et al.

Nature Communications, 2025

Structural plasticity of the FOXO-DBD:p53-TAD interaction.

Kohoutova K et al.

Nature Communications, 2025

40425537 (PubMed )
Supplement: 41467_2025_59106_MOESM1_ESM.pdf

Multiple regulatory intrinsically disordered motifs control FOXO4 transcription factor binding and function.

Bourgeois B et al.

Cell Reports, 2021

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