Associated Papers
Missense variants in human forkhead transcription factors reveal determinants of forkhead DNA bispecificity.
King J et al.
Cell Reports, 2025
Z-flipon variants reveal the many roles of Z-DNA and Z-RNA in health and disease.
Umerenkov D et al.
Life Science Alliance, 2023
The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
Leng F et al.
Immunity, 2022
A Structure-Guided Delineation of FOXP3 Regulation Mechanism in IPEX.
Ma T et al.
Advances in Experimental Medicine and Biology, 2021
Molecular feature and therapeutic perspectives of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.
Huang Q et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2020
Robust classification of protein variation using structural modelling and large-scale data integration.
Baugh EH et al.
Nucleic Acids Research, 2016
The immunological and genetic basis of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome.
Bin Dhuban K et al.
Current Opinion in Allergy and Clinical Immunology, 2015
Fetal-onset IPEX: report of two families and review of literature.
Xavier-da-Silva MM et al.
Clinical Immunology (orlando, Fla.), 2015
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Chen Y et al.
Nucleic Acids Research, 2015
FOXP3: genetic and epigenetic implications for autoimmunity.
Katoh H et al.
Journal of Autoimmunity, 2013
The immunogenetics of immune dysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome.
d'Hennezel E et al.
Journal of Medical Genetics, 2012
Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution.
Andersen KG et al.
Frontiers in Immunology, 2012
Immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome: a paradigm of immunodeficiency with autoimmunity.
Barzaghi F et al.
Frontiers in Immunology, 2012
Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells.
Bandukwala HS et al.
Immunity, 2011
Identification of new FOXP3 mutations and prenatal diagnosis of IPEX syndrome.
Harbuz R et al.
Prenatal Diagnosis, 2010
PhenoHM: human-mouse comparative phenome-genome server.
Sardana D et al.
Nucleic Acids Research, 2010
Digestive histopathological presentation of IPEX syndrome.
Patey-Mariaud de Serre N et al.
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2009
FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity.
Zhou Z et al.
Immunologic Research, 2008
FoxP3 enhances HIV-1 gene expression by modulating NFkappaB occupancy at the long terminal repeat in human T cells.
Holmes D et al.
The Journal of Biological Chemistry, 2007
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor.
Lopes JE et al.
Journal of Immunology (baltimore, Md. : 1950), 2006
Structural analysis of disease-causing mutations in the P-subfamily of forkhead transcription factors.
Banerjee-Basu S et al.
Proteins, 2004
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis.
Gambineri E et al.
Current Opinion in Rheumatology, 2003
IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena.
Bennett CL et al.
Current Opinion in Pediatrics, 2001
Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation.
Baud O et al.
The New England Journal of Medicine, 2001
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.
Wildin RS et al.
Nature Genetics, 2001