Varaico: Literature-Extracted Genetic Variants

Gene:FPR1
Variant:p.D71A
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FPR1

NM_002029.4:p.D71A

Associated Papers

Formyl Peptide Receptor Polymorphisms: 27 Most Possible Ways for Phagocyte Dysfunction.

Skvortsov SS et al.

Biochemistry. Biokhimiia, 2017

A single amino acid substitution (N297A) in the conserved NPXXY sequence of the human N-formyl peptide receptor results in inhibition of desensitization and endocytosis, and a dose-dependent shift in p42/44 mitogen-activated protein kinase activation and chemotaxis.

Gripentrog JM et al.

The Biochemical Journal, 2000

Identification of putative sites of interaction between the human formyl peptide receptor and G protein.

Miettinen HM et al.

The Journal of Biological Chemistry, 1999

The ligand binding site of the formyl peptide receptor maps in the transmembrane region.

Miettinen HM et al.

Journal of Immunology (baltimore, Md. : 1950), 1997

Binding of low affinity N-formyl peptide receptors to G protein. Characterization of a novel inactive receptor intermediate.

Prossnitz ER et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."