Associated Papers
IFNAR2 p.F8S Variant Associates with Severe COVID-19 and Adaptive Immune Cell Activation Modulation.
Malvestiti F et al.
International Journal of Molecular Sciences, 2026
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
Yu H et al.
Elife, 2024
Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
Yu H et al.
Biorxiv : the Preprint Server for Biology, 2023
Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.
Rajeh A et al.
Medrxiv : the Preprint Server for Health Sciences, 2023
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Barrio-Hernandez I et al.
Nature Genetics, 2023
Multidisciplinary In-Depth Investigation in a Young Athlete Suffering from Syncope Caused by Myocardial Bridge.
Brancaccio M et al.
Diagnostics (basel, Switzerland), 2021
Secreted frizzled-related protein 3 was genetically and functionally associated with developmental dysplasia of the hip.
Xu R et al.
Aging, 2021
Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.
Fontana D et al.
Hemasphere, 2020
Introducing the first whole genomes of nationals from the United Arab Emirates.
AlSafar HS et al.
Scientific Reports, 2019
Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status.
Fedirko V et al.
Nutrients, 2019
Association study of candidate genes for susceptibility to Kashin-Beck disease in a Tibetan population.
Tai Z et al.
Bmc Medical Genetics, 2017
Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3.
Oldefest M et al.
The Biochemical Journal, 2015
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Association between polymorphisms in sclerostin, dickkopfs and secreted frizzled-related protein genes and bone mineral density in postmenopausal Korean women.
Lee DO et al.
Gynecologic and Obstetric Investigation, 2014
An association-adjusted consensus deleterious scheme to classify homozygous Mis-sense mutations for personal genome interpretation.
Preeprem T et al.
Biodata Mining, 2013
Association of single nucleotide polymorphisms in Wnt signaling pathway genes with breast cancer in Saudi patients.
Alanazi MS et al.
Plos One, 2013
Integrating precision medicine in the study and clinical treatment of a severely mentally ill person.
O'Rawe JA et al.
Peerj, 2013
The association between polymorphisms in Wnt antagonist genes and bone response to hormone therapy in postmenopausal Korean women.
Kim H et al.
Menopause (new York, N.y.), 2012
Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis.
Baker-Lepain JC et al.
Arthritis and Rheumatism, 2012
Wnt pathway and IL-17: novel regulators of joint remodeling in rheumatic diseases. Looking beyond the RANK-RANKL-OPG axis.
Daoussis D et al.
Seminars in Arthritis and Rheumatism, 2010
No association of the polymorphisms of the frizzled-related protein gene with peak bone mineral density in Chinese nuclear families.
Gao G et al.
Bmc Medical Genetics, 2010
Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia.
Berndt SI et al.
Cancer Causes & Control : Ccc, 2009
WNT Signaling in osteoarthritis and osteoporosis: what is the biological significance for the clinician?
Lodewyckx L et al.
Current Rheumatology Reports, 2009
The contribution of genes to osteoarthritis.
Valdes AM et al.
The Medical Clinics of North America, 2009
Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts.
Kerkhof JM et al.
Osteoarthritis and Cartilage, 2008
Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis.
Corr M
Nature Clinical Practice. Rheumatology, 2008
Variation in the secreted frizzled-related protein-3 gene and risk of osteolysis and heterotopic ossification after total hip arthroplasty.
Gordon A et al.
Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society, 2007
The functional genetic variant Arg324Gly of frizzled-related protein is associated with colorectal cancer risk.
Shanmugam KS et al.
Carcinogenesis, 2007
Further evidence of the role of frizzled-related protein gene polymorphisms in osteoarthritis.
Rodriguez-Lopez J et al.
Annals of the Rheumatic Diseases, 2007
Allelic expression analysis suggests that cis-acting polymorphism of FRZB expression does not contribute to osteoarthritis susceptibility.
Snelling S et al.
Osteoarthritis and Cartilage, 2007
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee.
Valdes AM et al.
Arthritis and Rheumatism, 2007
Frizzled-related protein variants are risk factors for hip osteoarthritis.
Lane NE et al.
Arthritis and Rheumatism, 2006
Evidence for a differential association of the Arg200Trp single-nucleotide polymorphism in FRZB with hip osteoarthritis and osteoporosis.
Lories RJ et al.
Rheumatology (oxford, England), 2006
Polymorphism in signal transduction is a major route through which osteoarthritis susceptibility is acting.
Loughlin J
Current Opinion in Rheumatology, 2005
The genetic epidemiology of human primary osteoarthritis: current status.
Loughlin J
Expert Reviews in Molecular Medicine, 2005
Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites.
Min JL et al.
Arthritis and Rheumatism, 2005
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.
Loughlin J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004