Varaico: Literature-Extracted Genetic Variants

Gene:FSHR
Variant:p.D581G
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FSHR

NM_000145.4:p.D581G

Associated Papers

Functional characterization of naturally-occurring constitutively activating/inactivating mutations in equine follicle-stimulating hormone receptor.

Byambaragchaa M et al.

Animal Bioscience, 2022

Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.

Tao YX

Pharmacology & Therapeutics, 2008

Chimeras of the rat and human FSH receptors (FSHRs) identify residues that permit or suppress transmembrane 6 mutation-induced constitutive activation of the FSHR via rearrangements of hydrophobic interactions between helices 6 and 7.

Tao YX et al.

Molecular Endocrinology (baltimore, Md.), 2002

[A study on the role of the transmembrane V to VI regions of the human luteinizing hormone receptor in its constitutive activation].

Kudo M

[hokkaido Igaku Zasshi] the Hokkaido Journal of Medical Science, 1999

Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop.

Kudo M et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."