Varaico: Literature-Extracted Genetic Variants

Gene:FSHR
Variant:p.S273I
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FSHR

NM_000145.4:p.S273I

Associated Papers

Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor.

Duan J et al.

Nature Communications, 2023

Structure-Function Relationships of the Follicle-Stimulating Hormone Receptor.

Ulloa-Aguirre A et al.

Frontiers in Endocrinology, 2018

Structural biology of glycoprotein hormones and their receptors: insights to signaling.

Jiang X et al.

Molecular and Cellular Endocrinology, 2014

Critical involvement of the hinge region of the follicle-stimulating hormone receptor in the activation of the receptor.

Agrawal G et al.

The Journal of Biological Chemistry, 2009

Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.

Tao YX

Pharmacology & Therapeutics, 2008

Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues.

Bonomi M et al.

Molecular Endocrinology (baltimore, Md.), 2006

Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.

Montanelli L et al.

Molecular Endocrinology (baltimore, Md.), 2004

Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region.

Nakabayashi K et al.

The Journal of Biological Chemistry, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."