Varaico: Literature-Extracted Genetic Variants

Gene:FTH1
Variant:p.E62K
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FTH1

NM_002032.3:p.E62K

Associated Papers

Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study.

Bou-Abdallah F et al.

Biochemistry, 2002

Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism.

Corsi B et al.

The Journal of Biological Chemistry, 2002

Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

Cozzi A et al.

The Journal of Biological Chemistry, 2000

Evidence that residues exposed on the three-fold channels have active roles in the mechanism of ferritin iron incorporation.

Levi S et al.

The Biochemical Journal, 1996

Ferroxidase kinetics of human liver apoferritin, recombinant H-chain apoferritin, and site-directed mutants.

Sun S et al.

Biochemistry, 1993

Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.

Levi S et al.

The Biochemical Journal, 1992

Evidence that a salt bridge in the light chain contributes to the physical stability difference between heavy and light human ferritins.

Santambrogio P et al.

The Journal of Biological Chemistry, 1992

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."