Varaico: Literature-Extracted Genetic Variants

Gene:FTO
Variant:p.K45I
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FTO

NM_001080432.3:p.K45I

Associated Papers

Translating IBD Genomics into Clinical Practice.

Singh P et al.

Digestive Diseases and Sciences, 2026

Evaluation of FTO polymorphism in 6-mercaptopurine related intolerance in children with acute lymphoblastic leukemia.

Singh M et al.

Cancer Chemotherapy and Pharmacology, 2023

Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO's substrate binding implicated in obesity.

Kumar R et al.

Frontiers in Nutrition, 2022

35923209 (PubMed )
Supplement: Data_Sheet_1.PDF

Comparison of potential inhibitors and targeting fat mass and obesity-associated protein causing diabesity through docking and molecular dynamics strategies.

Kumar SU et al.

Journal of Cellular Biochemistry, 2021

Variants of Lipid-Related Genes in Adult Japanese Patients with Severe Hypertriglyceridemia.

Matsunaga A et al.

Journal of Atherosclerosis and Thrombosis, 2020

An intronic FTO variant rs16952570 confers protection against thiopurine-induced myelotoxicities in multiethnic Asian IBD patients.

Chen S et al.

The Pharmacogenomics Journal, 2020

A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD.

Kim HS et al.

Gut, 2017

Genome-Wide Association Studies of Chemotherapeutic Toxicities: Genomics of Inequality.

Mapes B et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

Prevalence of loss-of-function FTO mutations in lean and obese individuals.

Meyre D et al.

Diabetes, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."