Varaico: Literature-Extracted Genetic Variants

Gene:FTO
Variant:p.D233A
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FTO

NM_001080432.3:p.D233A

Associated Papers

FTO suppresses DNA repair by inhibiting PARP1.

Zhu T et al.

Nature Communications, 2025

AVCAPIR: A Novel Procalcific PIWI-Interacting RNA in Calcific Aortic Valve Disease.

Han D et al.

Circulation, 2024

m6A modification enhances the stability of CDC25A promotes tumorigenicity of esophagogastric junction adenocarcinoma via cell cycle.

Pan Y et al.

International Journal of Biological Sciences, 2024

m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation.

Nan Y et al.

Cell Reports, 2023

RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability.

Xiong F et al.

Cell Research, 2021

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing.

Bartosovic M et al.

Nucleic Acids Research, 2017

FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N6-Methyladenosine RNA Demethylase.

Li Z et al.

Cancer Cell, 2017

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.

Zhao X et al.

Cell Research, 2014

Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway.

Lin L et al.

Human Molecular Genetics, 2014

Screening for coding variants in FTO and SH2B1 genes in Chinese patients with obesity.

Zheng Z et al.

Plos One, 2013

Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites.

Müller TA et al.

Dna Repair, 2010

Mapping and significance of the mRNA methylome.

Sibbritt T et al.

Wiley Interdisciplinary Reviews. Rna, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."