Varaico: Literature-Extracted Genetic Variants

Gene:FURIN
Variant:p.D153N
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FURIN

NM_002569.4:p.D153N

Associated Papers

Autocatalytic activation of the furin zymogen requires removal of the emerging enzyme's N-terminus from the active site.

Gawlik K et al.

Plos One, 2009

Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage.

Leduc R et al.

The Journal of Biological Chemistry, 1992

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."