Varaico: Literature-Extracted Genetic Variants

Gene:FUS
Variant:p.S148R
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FUS

NM_004960.4:p.S148R

Associated Papers

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.

Guo L et al.

Molecular Cell, 2026

Splicing factor FUS facilitates the progression of PIT1-lineage PitNETs by upregulating MDM2.

Wang X et al.

Theranostics, 2026

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.

Guo L et al.

Biorxiv : the Preprint Server for Biology, 2023

Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models.

Cha SJ et al.

Developmental Cell, 2022

The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage.

Mastrocola AS et al.

The Journal of Biological Chemistry, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."